Introducing the next-generation Pharmaceutical Lyophilizer Freeze Dryer for Pilot Plant – engineered to bridge R&D and full-scale production with unmatched reliability.
Designed for biotech firms, CDMOs, and research facilities, this GMP-compliant pharmaceutical freeze dryer delivers cGMP-ready lyophilization for vaccines, biologics, and injectables.
Tray area: 0.2~1.05㎡
Cold trap temperature: -70℃
Vacuum Degree: <5Pa, no load
Handling capacity: 3kg ~16kg/batch
Heating method: electrical heating and others heating method.
Our pilot freeze dryers especially simplify the operation of small freeze-drying machine, prevent the pollution of the material, and control the moisture sublimation of the material .
The series have shelf cooling and heating, can be programmed, and can view the freeze-drying curve. It is very convenient for users to observe the freeze-drying process of the material.
Working Principle of Pharmaceutical Freeze Dryer
Freeze-drying refers to the method of freezing the water-containing substance into a solid state first, and then sublimating the water directly from the solid state into a gas state under a certain vacuum degree to remove the water and preserve the substance.
The basic principle of freeze-drying is based on the change of three states of water. Since water has a solid, liquid and gas state, and the three states can be converted into each other and can coexist.
When water is at the triple point (temperature is 0.01℃, water vapor pressure is 610.5Pa), water, ice and water vapor can coexist and balance each other.
And when the pressure is lower than 610Pa, no matter how the temperature changes, the liquid state of water cannot exist.
In a high vacuum state, using the principle of sublimation, the moisture in the pre-frozen material is directly sublimated into water vapor in an ice state and removed without melting the ice, so as to achieve the purpose of freeze-drying.
Technical Specifications
Features of Pilot Freeze Dryer
- In-situ pre-freeze drying, one-button start operation.
- Temperature is adjustable, vacuum is adjustable, production process is controllable.
- Equip with an inflation valve, it can be filled with dry inert gas.
- Heat transfer oil heating, high temperature control accuracy, tray temperature difference is ≤1℃, uniform drying effect.
- The drying room adopts high ligh transmission, colorless and transparent plexiglass door, which can be cleaned to observe the change process of materials during operation.
- PLC control system, touch screen, display drying curve and USB data storage interface. It can store multiple programs, each program can be set to 36 segments, program parameters can be modified during operation, and vacuum drying curves and data can be recorded and exported.
Application
- Biological field: such as serum, plasma, antibodies, vaccines, drugs, microorganisms, plant extracts for biological research and other freeze-drying
- Non-biological field of nanoparticles, colloids, powders, food, plants, cultural relics drying.