Soxhlet quotations go wrong when buyers provide only: “I need a Soxhlet extractor, please quote.”
A quote becomes accurate only when the supplier can size:

  • extraction chamber and loading method

  • reflux rate & cycle frequency targets

  • condenser duty and cooling utilities

  • solvent recovery and reuse strategy

  • safety scope (explosion-proof, inerting, interlocks)

  • downstream integration (filtration, concentration, drying)

If you’re new to the method, read this first: Soxhlet Extraction: Lab vs Industrial, How It Works & When to Use It

Copy/Paste RFQ Checklist (send to suppliers)

A) Material & product goals (must-have)

  1. Material name and description

    • plant/botanical name (or solid sample type)

    • form: cut / powder / granule / resinous chunks

    • moisture level (dry / semi-dry / wet; % if known)

  2. Target compounds

    • what you want to extract (e.g., oils, resins, phenolics, caffeine, etc.)

    • any compounds you want to avoid (chlorophyll, waxes, sugars)

  3. Final product form

    • crude extract / concentrated paste / dry powder / purified fraction

    • quality requirements: color, odor, impurity limits, residual solvent targets

B) Solvent system & constraints (must-have)

  1. Preferred solvent(s)

    • single solvent or blend (if known)

    • solvent restrictions: food grade / pharma / local regulatory limits

  2. Solvent selection intent

    • goal is “exhaustive extraction” or “selective extraction”?

    • any previous experience (too green, too viscous, low yield)

  3. Safety notes

    • flammable/toxic solvent? special storage restrictions?

    • can you use nitrogen blanketing if required?

Related reading (solvent selection):
Soxhlet Solvent Selection: Polarity, Boiling Point & Safety

C) Capacity & throughput (must-have)

  1. Batch size target

    • kg of dry material per batch (or liters of packed volume)

  2. Daily throughput target

    • kg/day or batches/day and operating hours/day

    • whether you run 5 days/week or 24/7

  3. Scale type

    • lab / pilot / industrial production

    • if pilot: is it for process validation or long-term small production?

D) Performance targets (highly recommended)

  1. Extraction endpoint criteria

  • time-based (hours) OR preferred: cycle-based / assay-based endpoint

  • do you have assay method (HPLC/GC/UV) for “plateau” confirmation?

  1. Target reflux rate or cycle frequency (if known)
    If you have lab data, provide:

  • reflux rate (mL/min or drops/sec)

  • average cycle time (min/cycle)

  • cycles/hour and total cycles

If you don’t have this yet, ask supplier to propose a target based on your material and solvent.

Related reading (cycle control):
How to Control Soxhlet Cycle Time: Reflux Rate, Siphon Frequency & Yield

E) Utilities available (must-have for accurate sizing)

  1. Electrical supply

  • voltage / phase / frequency (e.g., 380V/50Hz, 220V/60Hz)

  1. Cooling source for condenser

  • tap water / chilled water / recirculating chiller

  • available cooling water temperature range and flow capacity (if known)

  1. Vacuum availability (if downstream concentration is needed)

  • do you have a vacuum pump or need it included?

Related reading (downstream concentration):
vacuum concentration for botanical extracts

F) Solvent recovery & reuse (must-have for industrial)

  1. Do you need solvent recovery?

  • yes/no

  • target recovery % expectation (if you have a goal)

  1. Recovered solvent quality requirements

  • reuse in same batch? reuse across products?

  • water content limits? contamination concerns?

  1. Solvent storage & transfer preference

  • open transfer vs closed transfer

  • storage tank requirements (volume, material)

G) Safety scope (critical for pilot/industrial)

  1. Installation environment

  • indoor/outdoor, ventilation quality, room size

  • hazardous area classification (if defined)

  1. Explosion-proof scope requirement

  • required by your site or local regulations? (yes/no/unknown)

  1. Safety interlocks and automation

  • cooling interlock, low level shutdown, high temp trip, alarms, data logging

  • manual / semi-auto / PLC recipe operation

Related reading (safety):
Soxhlet Safety: Solvent Handling, Explosion-Proof Design & Interlocks

H) Materials of construction & cleanliness

  1. Preferred material

  • SS304 / SS316L / glass (lab)

  • seal material preference if known (PTFE, FKM, etc.)

  1. Cleaning requirement

  • manual cleaning acceptable?

  • do you need CIP-like cleaning logic? (rare for Soxhlet, but possible in integrated skids)

I) Documentation & services (avoid misunderstandings)

  1. Documentation required

  • datasheet + GA drawing

  • PFD / P&ID

  • electrical drawings

  • interlock list

  • manuals (O&M), spare parts list

  1. Factory testing & acceptance

  • FAT (factory acceptance test) required?

  • what performance must be demonstrated (cycle stability, leak test, recovery rate)

  1. Installation/commissioning

  • remote guidance or on-site?

  • operator training required?

“Minimum RFQ” Template (if you want a short email)

Copy/paste this if you want the shortest message that still gets an accurate quote:

  • Material: ____ (form, moisture, particle size)

  • Target compound(s): ____ ; avoid: ____

  • Solvent preference/restriction: ____

  • Batch size: ____ kg/batch; throughput: ____ kg/day

  • Endpoint: ____ (hours or cycles or assay target)

  • Utilities: power ____; cooling water/chiller ____

  • Need solvent recovery: yes/no; reuse requirement: ____

  • Safety scope: indoor/outdoor; explosion-proof requirement: ____

  • Documentation: ____ (GA/PFD/P&ID/FAT/etc.)

FAQ (with answers)

1. Why do you need particle size and moisture for a Soxhlet quote?

They affect bed resistance, swelling behavior, and cycle time stability—critical for sizing chamber volume, thimble media, and target reflux rate.

Because Soxhlet performance is driven by reflux–siphon cycles, not just total hours. Cycle metrics help ensure repeatable yield.

Condenser sizing and stable reflux depend on coolant temperature and flow. Insufficient cooling is a major failure cause (vapor escape, solvent loss).

Only roughly. Industrial economics and safety depend heavily on solvent recovery design and reuse strategy.

Throughput rhythm (batches/day), solvent restrictions, and safety scope (explosion-proof/interlocks).

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